Fullmetal Alchemist (2003)

'Fullmetal Alchemist' is a Japanese manga and anime series, created by Hiromu Arakawa, the manga serialised between 2001 to 2010. The story is set in the country Amestris in a world where alchemy is a main science. Brothers Edward and Alphonse Elric go on their journey to restore their bodies when an attempt to revive their mother backfired. An anime adaptation, simply titled 'Fullmetal Alchemist', was made during the manga's run, lasting 51 episodes, diverging significantly from the source material's plot.

E43: The Stray Dog
Valmon and Breda try to apprehend Edward and Alhponse, but Edward manages to incapacitate them by inflating their uniforms until they're spherical, allowing the brothers to escape.